Soft tissue tumors - Histopathological study of 93 cases

القسم: Article
منشور
Jun 24, 2025
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92-98

الملخص

Objective: Histopathological and immunohistochemical examination of soft tissue tumors to assess the value of these techniques in verifying the primary diagnosis and their classification.
Methods: A prospective study of 93 consecutive soft tissue biopsies that reached the department of histopathology, central labs, Dohuk, and application of immunohistochemical markers on 27 biopsies.
Results: Out of 93 soft tissue tumors, 70 (75.2%) were benign with mean age 27.6 y. and 23 cases (24.8 %) were malignant with mean age 39.1 y.. Immunohistochemistery was performed in 27 cases; 21 (77.7%) cases of malignant tumors and 6 (22.3%) benign cases. The most common benign tumors were Lipoma, Haemangioma, Neurofibroma, while malignant muscle tumors (leiomyosarcoma and Rhabdomyosarcoma) and malignant round cell tumors (Ewing’s sarcoma/ PNET) were the major groups .
Conclusion: High quality H and E stained section, remain the best method for establishing the primary diagnosis of soft tissue tumors, but immunohistochemical examination proved extremely helpful in sub classifying them, where 7 out of 9 cases of gastrointestinal tumors (GISTs) showed strong immunoreactivity with (c – kit proteins) CD117, CD34, while other (non GISTs) tumors were negative.

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الإحصائيات

كيفية الاقتباس

1.
S. Hasan I, S. Hasan I, Y. Suliman A, Y. Suliman A, A. Hassawi B, A. Hassawi B. Soft tissue tumors - Histopathological study of 93 cases. Ann. coll. Med. Mosul [انترنت]. 24 يونيو، 2025 [وثق 3 أغسطس، 2025];36(1):92-8. موجود في: https://rjps.uomosul.edu.iq/index.php/mmed/article/view/14988