Effect of combined oral contraceptive pills on some haemostatic parameters

القسم: Article
منشور
Jun 24, 2025
##editor.issues.pages##
66-69

الملخص

Objective: To assess our local status of markers of coagulation in response to combined oral contraceptive (COC) pill.Methods: A prospective clinico- haematological study was carried out in private lab. Forty non smoker women on (COC) pill ( Levonorgestrel 0.25 mg and ethinyl estradiol 0.05mg) for 3 months and more; their ages ranging between thirty and thirty five with a control group of 40 women were studied during a period of 6 months starting from August 2006. Most important haemostaic parameters including platelet count (PC) Prothrombin time (PT) and activated partial thromboplastin time (APTT), Fibrinogen and D-dimer were done for them.Results: There was a significant increase in the mean values of (PC), fibrinogen with (P <0.05, <0.05) respectively, while the PT and APTT were significantly reduced with (P <0.05, <0.05) respectively. D-dimer was significantly positive in users than non users (P<0.001).Conclusion: there was some degree of pro-coagulant activity in women on COC and such females need monitoring of haemostatic parameters.

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كيفية الاقتباس

1.
A. Kashmoola M, A. Kashmoola M, J. AL-Husaynee A, J. AL-Husaynee A. Effect of combined oral contraceptive pills on some haemostatic parameters. Ann. coll. Med. Mosul [انترنت]. 24 يونيو، 2025 [وثق 3 أغسطس، 2025];33(1):66-9. موجود في: https://rjps.uomosul.edu.iq/index.php/mmed/article/view/15331