Abstract The honorable and holy creature in which God breathed his soul and the highest affairs among all creatures. His blood, honor and fortune are protected, and man was subjected by his brother in humanity to the most heinous methods of annihilation and death. The Quran and the Bible and the holy book - the Old and New Testaments - recorded and documented numerous events of collective annihilation. People were subjected to it, either out of religion, race, revenge, envy and hatred, or out of power and taking control of matters, so this paper was an academic study to dive into the depths of the Holy Quran and the Bible to answer questions on this subject and came out as follows: The first unit we talked about the concept and rule of genocide in the Holy Quran and the Bible, and the image of documenting the Holy Quran and the book of genocide, and in the second unit we explained the motives that led to the genocide and clarify its dire effects, according to the Holy Quran and the Bible, and finally we stopped on the most important ways and routes to prevent The occurrence of genocide, or to block the way in front of it. We reached the following main points: -Genocide, a criminal process carried out by a group or individuals against a group, origin, religion or idea, and pictures of those operations are mentioned in the legal definition thereof. - Genocide was forbidden by the Holy Quran and attacked clearly, and the Bible prohibits killing and calls for peace, but sometimes calls for genocide - especially - out of revenge. - The Bible is full of documenting the genocides in the Old and New Testaments. - The motives for the genocide are multiple, the most important of which are revenge, hence envy and seizure of power. The most prominent recommendations that we reached are: - Islamic advocates and other religious scients should criminalize bloodshed and attack humiliating human dignity. - We call upon the workers in the media to cover up crimes, to support public opinion against it and to exaggerate it, so as not to lead to genocide. - Religion is a positive factor in all cases. If used correctly to suppress ideas and introductions to genocide, we call for maximum benefit from religion to build society.