Volume 18 Issue 2

Published: 2025-06-25

Contents


Research Paper
Preparation and Evaluation of Topical Gel Containing Aloe Vera Exudate

Amina M. Al-Nima

Background:Aloe vera is known as a miracle plant belonging to the Lily (Liliaceae) family, The exudate of Aloe vera is utilized as a natural drug as it can be used for many medicinal purposes.Aims:...

Pages: 39-52
Formulation and Evaluation of Rosuvastatin Calcium Polymeric Nanoparticles-Loaded Transdermal Patch

Mais S. Saadallah, Omar A. Hamid

Background: Transdermal drug delivery systems (TDDS) have been rapidly developed as a promising alternative to the oral delivery systems to provide controlled drug delivery and avoid the first-pass...

Pages: 22-38
Antibacterial activities of plant extract Cinnamomum zeylanicum bark against multidrug-resistant bacteria

Nishteman F. Mohammad, Shilan S. Saleem, Rand B. Balata, Dian J. Salih

Background : Due to the increased occurrence of bacterial resistance to multiple antimicrobial drugs, there is a constant search for novel therapeutic strategies; medicinal plants represent an...

Pages: 10-21
Evaluation of cytogenetic damage induced by antihypertensive drug Amlodipine: in vitro

Dian J. Salih, Sayran K. Salih, Rawaa M. Abdo, Asaad A. Alasady

Background: Amlodipine is a calcium channel blocker medication used to treat high blood pressure and coronary artery diseases for long term of use. Sufficient studies reporting the cytogenetic...

Pages: 1-9
Review Paper
Minoxidil in androgenic alopecia: New formulations with Improved delivery

Hani Almukhtar, Alaa Al-taie, Myasar M. Al-kotaji

Background: Minoxidil was introduced into the market as a hypotensive agent, however, aftermarketing, the hypertrichosis side effect was reported by almost all users. This adverse effect encourages...

Pages: 53-63
Drug Abuse as a Contemporary Social Problem

Zena S. Hamed,

Objective: Drug abuse and its repercussions are of the most serious problems in society nowadays. This is because of their enormous influence on the individual, the family, and its social effects...

Pages: 194-202
Transdermal patch of acetylsalicylic acid as an alternative dosage form: A review

Mohanad A. Alfahad, Hayder F. Alhamdany

As a substitute for traditional systemic administration, many topical treatments have lately evolved. Transdermal drug delivery systems (TDDSs) are the most appealing of these methods due to their...

Pages: 64-72
Bacteriophage as a Promising Alternative or Complementary Therapy to Antibiotics

Zahraa A. Hashim, Farah H. Omer

The global issue of antibiotic resistance and the narrowing down of new antibiotic discoveries besides their cost has led to the reintroduction of bacteriophage as a focus of research projects....

Pages: 84-96
Effect of polyphenol secondary metabolites on oxidative stress and inflammatory responses associated with aging diseases

Maimonah Qasim Yahya, Khadeeja Y. Abid, Adnan A. Zainal

Several mechanisms are responsible for regulating the process of aging. A rise in reactive oxygen species (ROS) and oxidative stress is usually linked to the development of age-related diseases....

Pages: 73-83
Synthesis of coumarin-based derivatives from different starting materials: A review of ongoing developments

Sarah A. Waheed, Yasser Fakri Mustafa

Objective: This brief review highlights the recent advances in the synthesis of coumarin-based derivatives from phenols, aldehydes, ketones, and various other functional group-containing starting...

Pages: 126-138
A review on coumarin backbone: An attractive scaffold for promising bioactive compounds

Yasser Fakri Mustafa, Sara F. Jasim

Background: Coumarin moiety is found in many naturally occurring products that have been used for many decades in traditional medicine around the world. Coumarin has distinctive physicochemical...

Pages: 104-125
Coumarin-based products: Their biodiversity and pharmacology

Harith Al-Qazaz, Yasser Fakri Mustafa, Reem N. Ismael

Background: The plant kingdom generates and releases a wide range of secondary-metabolites, which have several effects on biological, toxicological, and ecological systems that may act in a similar...

Pages: 162-179
Natural Coumarin-Lead Compounds: A Review of Their Medicinal Potentials

Yasser Fakri Mustafa, Rahma M. Jebir

Background: Natural coumarins group, a principal member of the benzopyrone family, is one of the naturally occurring substances obtained ordinarily from plant origins, with antibacterial,...

Pages: 139-161
Green synthesis of Schiff bases: a review study

Ahmed A. Mahmood

Objectives: Green chemistry is the field that implies instruments and procedures, by which it offers significant environmental and financial benefits above traditional synthetic methods. The modern...

Pages: 180-193
Drug Physicochemical Properties Relevant to Powder Flowability in Pharmaceutical Appliance: A Review

Liqaa S. Esmail

Background: Studies have shown that the powder flowability rate significantly impacts the content uniformity and weight of the active pharmaceutical ingredients in drug tableting procedures.The aim...

Pages: 97-103