Volume 11 Issue 2

Published: 2025-06-25

Contents


Article
Cerebrospinal fluid cholinesterase activity in children with meningitis

Aldeen Alnoori, Mohammed Khalid Jamal,

Objective: To assess the changes of cerebrospinal fluid (CSF) acetyl cholinesterase(AChE) activity in children with acute bacterial meningitis in comparison to healthyage and sex matched...

Pages: 70-76
Assessment of serum carcinoembryonic antigen in colorectal cancer patients treated by surgery and chemotherapy

Shahbaa A. Al-Bayati,

Objective: Carcinoembryonic antigen (CEA) is a protein found in many types of cellsassociated with tumors and the developing fetus. The main use of CEA is as a tumormarker, especially with...

Pages: 12-16
Synthesis of new metoclopramide derivatives and in vitro evaluation of their human cholinesterases protection against Chlorpyrifos

Islam Tarik Qasim, Ahmed A.J. Mahmood, Yasser Fakri Mustafa,

Objective: The purpose of this study was to synthesize three new derivatives ofmetoclopramide by diazotization and replacement reactions and then to quantify invitro their protection effects on...

Pages: 58-69
Comparison between quantitative and qualitative biochemical markers in the diagnosis of acute coronary syndrome

Akram J Ahmad, Samir B Al-Mukhtar,

Objectives: To compare between the qualitative estimation of biochemical markersPoint-of-Care testing) with the quantitative estimation of the same markers in thediagnosis of acute coronary...

Pages: 102-110
Effects of estrogen replacement therapy on symptoms and clinical parameters in post menopausal women

Norjihan Ali Shaban, Kawa Dizaye,

Objective: To evaluate the effect of oral estrogen replacement therapy (ERT) in healthypostmenopausal women on lipid profile, body mass index (BMI), blood pressure, andblood glucose; and on...

Pages: 46-57
Preparation of modified release diltiazem HCl capsule by complexation with ion exchange resin

Eman B.H. Al-Khedairy, Alaa A. Abdulrasso, Jenan M. AL-Mosawi,

Background: Diltiazem HCl is a calcium channel blocker drug used in the treatmentof angina pectoris and hypertension.Objective: To prepare a sustained release diltiazem HCl capsule by...

Pages: 17-26
The effect of rifampicin and isoniazid on liver and lung tissues in rats

Dalal F. Ahmed,

Objectives: The purpose of this study was to investigate the histopathologicalchanges in Swiss albino rats liver and lung tissues resulted from the oraladministration of the antituberculous drugs...

Pages: 34-45
The effect of antioxidant supplementation in the treatment of epilepsy

Nazar A.K. hamid,

Aim: To assess serum level of malondialdehyde (MDA) and total antioxidant status(TAS) as a representative of oxidative stress in patients with generalized epilepsy andto evaluate the therapeutic...

Pages: 27-33
Indirect spectrophotometric method for the determination of bisacodyl in commercial dosage forms and in environmental water samples

Nawal A. Majid, Nief Rahman Ahmad,

Objective: A simple, sensitive, and accurate indirect spectrophotometric method forthe determination of bisacodyl in pure form and in some of its pharmaceuticalpreparations.Method: The method is...

Pages: 77-84
Serum immunoglobulin levels in male schizophrenic patients before and after olanzapine therapy

Mahmoud Khudhayer Oglah Hussein,

Objective: To evaluate the effect of olanzapine therapy on serum immunoglobulinlevels (IgA, IgG, IgM) in male schizophrenic patients after 2 months of treatment byolanzapine at a daily dose of 20...

Pages: 111-114
Synthesis and in vitro kinetic study of novel mutual azo prodrug for inflammatory bowel disease

Yasser Fakri Mustafa,

Background: Inflammatory bowel disease (IBD) refers to idiopathic inflammatorydiseases of the intestine, principally ulcerative colitis and Crohns disease. IBD ischaracterized by chronic...

Pages: 1-11
Detection of Toxoplasma gondii IgM and Cytomegalovirus IgM antibodies among blood donors in Mosul

Karam A. Al-Dabbagh,

Background: Toxoplasmosis is an infection caused by the protozoan parasiteToxoplasma gondii. This parasite can be transmitted via blood transfusion.Cytomegalovirus (CMV) is a herpes virus that can...

Pages: 85-92