Evaluation of the correlation between the hormone adiponectin and vitamin D3 in obese women
Section: Original Articles
Abstract
The research included a study of the relationship between the hormone adiponectin and vitamin D3 in obese female patients. The results we obtained showed that the level of the concentration of the hormone adiponectin shows a high significant decrease in the blood serum of obese patients compared to a control sample of healthy women. The results also showed that the level of vitamin D3 concentration shows a significant decrease It was high in the serum of obese patients compared with control samplesKeywords: Delayed Cord Clamping, Neonatal Outcomes. Hematocrit, Hemoglobin, Total Serum Bilirubin, and hematological parameters.
References
- ,
- , and its deficiency is associated with musculoskeletal and cardiovascular disorders, as well as autoimmune, dermatological, and cancer diseases [12, 13]. Furthermore, serum vitamin D levels appear to be related to obesity in both healthy and ill individuals
- ,and preclinical studies showed that adiponectin has an anti-inflammatory function in Lung cells (Garcia & Sood (2012)) It is a vasodilator and reduce the inflammatory mechanism
- ,and that adiponectin is closely related to obesity, but a decrease in plasma adiponectin is a cause of increased obesity. The decrease in adiponectin for patients does not appear to be a predictor of future body weight gain.
- ,Hossein-Nezhad et al stated that vitamin D deficiency D3 leads to a higher incidence of autoimmune and cardiovascular diseases and cancer
- ,The synthesis of vitamin D3 in human skin is one of the factors that determines the amount of cholecalciferol available to healthy individuals.Many factors, including air pollution, lifestyle, use of The sun filters, and doses the ultraviolet rays thrown onto the makeup
- .
- A recent cohort study showed that higher concentrations of Adiponectin in the serum are associated with cancer and cancer-related deaths, which means that the paradox of Adiponectin contributes to the risk of cancer during aging
- . Adiponectin levels have been shown to increase with weight loss
- . Similarly, low adiponectin levels have also been found in women with endometriosis
- . The main circulating metabolite of vitamin D is vitamin 25(OH)D, which accurately reflects the amount of vitamin D in the body, whether it originated from food or was synthesized in the skin. According to many authors, vitamin D deficiency is a worldwide phenomenon that may affect as many as 3050% of the adult population
- . The reduced bioavailability of vitamin D is observed in overweight and obese individuals, which probably results from the increased sequestration of this vitamin in adipose tissue
- . Those especially prone to vitamin D deficiency are elderly people, due to their decreased ability to synthesize this vitamin in the skin
- . Until recently, vitamin 25(OH)D was regarded as a factor regulating calcium phosphate and bone tissue metabolism. Reports from recent years have confirmed that it is involved in maintaining homeostasis in many tissues
- . Vitamin D deficiency is closely related to visceral obesity
- and is typically found at levels 35% lower in men than in women. However, adiponectin concentrations are lower in women under certain conditions. Cnop and colleagues
- found no significant differences. Data on adiponectin concentrations in obese women are more robust, where adiponectin concentrations in adipose tissue and the circulation have consistently been found to be abnormally low
- found that postmenopausal women showed significantly higher adiponectin levels compared with premenopausal women, while Nishizawa and Colleagues