Impact ofCigarette Smoking on Ovarian Cancer inSulaimani City

BackgroundSmoking is a risk factor for mucinous ovarian cancer, but its effects on other ovarian cancer subtypes and on overall ovarian cancer risk are unclear. Methods This study was a case control study; it was conducted in Hiwa hospital for oncology in Sulaimani city. This study conducted from the 1st of June, 2019 to 1st of April 2020, involving 100 ovarian cancer patients and 100 female appeared normal without ovarian cancer as a controls. All subjects who agreed to participate signed a consent form, answered a data collection sheet about personal information as age, education, marital state ,education, economic status , physical activity and special habits especially exposure to passive smoking. Results The mean age of the examined subjects wss 44.9 13.9 and 37.9 13.7 for both cases and control groups respectively, with a significant difference (p< 0.001) Most cases were house wife 65% and 32% were illiterate with high significant difference (p< 0.001). 40 % of cases were Sufficient economic state . About cigarette smoking (5% , 3%)of women were active, (2%, 0%) quit, and (31%, 16%) passive smokers and the remaining( 62%, 81%) were never smokers in case and control groups respectively . So passive women more prone to ovarian cancer with a significant difference p =0.02 Especially those with > 5 years passive smoker (87.1%) comparing with 5 years and less in cases group and compared to control groups p< 0.001 . This study revealed that passive smoking was associated with serous ovarian cancer(15.5%). Majority of the patients complained from abdominal pain and abdominal distension (76%) as the first presenting symptom . Conclusions the mean age of Ovarian cancer woman was 44.9 13.9 and most of the age of patients had ovarian cancer were between 40-50 Years. Passive smoker women more prone to ovarian cancer especially those with > 5 years passive smoker . Passive cigarette smoking may be associated with serous ovarian cancer. Keywords: Age, Cigarette smoking, sign &symptom