Analysis of Hematological and Biochemical Parameters in Patients with Rheumatoid Arthritis in Sulaymaniyah

Section: Original Articles
Issue
Vol. 12 No. 1 (2024): Volume 12 Issue 1
Published
Jan 12, 2024
Pages
144-152

Abstract

Background: Rheumatoid arthritis (RA) is a chronic immune-mediated systemic inflammatory disease characterized by chronic synovial inflammation and hyperplasia, which drive joint erosion and damage, and a variety of systemic manifestations, which contribute to the overall burden of the disease, certain environmental and/or genetic risk factors can lead to the awakening of systemic autoimmunity. For this reason, this current research is designed to investigate some haematological and biochemical parameters in patients with rheumatoid disease in the Kurdistan region. Methods The investigation included healthy groups of 50 healthy people (21 men and 29 women) and 162 patients with rheumatoid disease (43 men and 119 women). The disease was diagnosed at Shahid Dr Hemn Hospital and Smart Health Tower from October 2022 to December 2022. SPSS statistical software (Version 20) (social science statistical package) was used to analyze the data. Differences in mean values between 2 groups were analyzed by two samples' t-tests (independent student's t-test). Results The results highlighted that rheumatoid disease was significantly correlated with age, sex, and daily exercise. Haematological markers (WBC, HGB) changed significantly, and inflammatory markers (ESR, CRP) also increased significantly in the rheumatoid disease groups in both genders.Conclusion: This study found that rheumatoid disease induces alterations in a majority of physiological and haematological markers within the body. Elevated levels of inflammation markers, particularly in individuals with rheumatoid disease, were associated with noticeable manifestations such as joint swelling, stiffness, or redness.

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Authors

Kaniaw Khafar

Department of Nursing, Halabja Technical Institute, Sulaimani Polytechnic University, Sulaimani City, Iraq.

ORCID
Meer Karim

Department of Medical Laboratory, College of Health and Medical Technology, Sulaimani Polytechnic University, Sulaimani City, Iraq

Nma Qadr
Saya Noori
Savia Mohammed
Shady Salah

Identifiers

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