Determination of Copper and Zinc in Blood and Tissues of Benign and Malignant Breast Tumors in the City of Mosul

Eighty six blood samples and thirty two of female breast tissues had been collected (benign and malignancy) also twenty samples as control groups included. Samples had been obtained from Hazim Al-Hafed Hospital for Tumors and Al-Zahrawi Hospital (Breast Disease Center).
The study included also measurement of Cu+2, Zn+2 and Cu/Zn ratio. The results showed significant increase in concentration of Copper and decrease in Zinc concentration in the female serum samples with breast cancer and significant increase in Cu/Zn ratio.
The results show significant increase in Zn+2 and Cu+2 concentration in booth benign and malignant tumor. The ratio of Cu/Zn had been significantly increased in malignant tumor and significant increase in Zn+2 and Cu+2 in the third stage of the tumor.