In Vitro Effects of Ethanolic Extract and Crude Alkaloids of Prosopis farcta Leaves on the Viability of Echinococcus granulosus Protoscolices in Comparison to Mebendazole

The scolicidal effects of crude ethanolic extract and crude alkaloids of Prosopis farcta leaves on protoscolices of Echinococcus granulosus were appraised in vitro, in comparison with mebendazole (the drug of choice in the treatment of echinococcosis) at 37C0 and 4C0 and at different time intervals.
Both extracts exerted higher effect at 37C0, and the crude alkaloids were more effective than ethanolic extract as it gave a scolicidal effect especially at the lower concentrations used (62.5, 31.2 mg/ml) within shorter periods (3 days and 13 days at 37C0 and 4C0 respectively)