Genetics of Resistance to the Fungicide Hymexazol in Aspergillus amstelodami

A samle of 84 mutants resistant to the fungicide Hymexazol were isolated in the parental strains A76 (bwA nicA) brown conidia, nicotinic acid requiring and AZG131 (wA lysA azgA) white conidia, lysine requiring and resistant to 8-azaguaninc of the ascomycetour fungus Aspergillus amstelodami. All mutants exhibited partial dominance to their respective wild type alleles and complementation tests in heterokaryons put them all into a single gene designated hymA as the first gene of its kind to be identified in this species. Haploidization analyses failed to locate hymA on any of the seven (I-VII) linkage groups recognized in this fungus although its linkage to the other two recognized groups(VIII and IX) was not tested due to inavailability of suitable master strains at the time.