Synthesis of Some Quinazolines and Imidazolo-[1,5-a]-3,1-benzoxazine-4-one Derivatives

Some substituted N-methylene-2-(3,1-benzoxazonyl-4-one) amide (3a-c) were prepared from reaction of acetic anhydride with N-acyl anthranilic acid (2a-c) was synthesized from anthranilic acid with acyl glycinyl chloride. Treatment of (3a-c) with POCl3 gave imidazolo-[1,5-a]-3,1-benzoxazin-4-one (4a-c).
Quinazoline derivatives (6a-c) were prepared by reaction of methyl anthranilate with imidoyl chloride, the resulting esters were then converted to the hydrazides (7a-c). The synthesized compounds were identificated by IR and UV spectra.