Effect of Zingiber Officinale Rhizomes Powder on Some Physiological , Histological and Biochemical Features in White Male Rabbits

This study was conducted to investigate the effect of Zingiber officinale rhizomes powder in some physiological, histological and biochemical features (7-8) months old in white male rabbits, Rabbits were divided into 2 groups (6 rabbits for each group). The first group was given the standard ration and normal water, the second group was given Zingiber officinal powder (1000 mg/kg) ration daily for 4 weeks. Results showed that the treatment with Zingiber officinale's powder caused a significant decrease in glucose, cholesterol and triglycerides a swell as a significant decrease in lowdensity lipoprotein LDL-C level, and increase in highdensity lipoprotein HDL-C level in blood serum, as well as increase of testosterone hormone level in comparison with control group. Histological sections showed some changes of liver tissue as swelling of hepatic cells, enlargement of centeral vein diameter. The testes showed increasing of cell layers lining the seminiferous tubules and increasing of leydig cells number. The adrenal gland showed an appearance of large sinusoids in each of Zona - Fasiculata and Zona reticularis of the cortex.