Investigating the Combined Effect of Silver Nanoparticles Prepared from Aloe Vera with Some Antibiotics on the Pathogenic Bacteria Shigella sp and Salmonella sp

The purpose of this study was to evaluate the efficacy of silver nanoparticles (AgNPs) prepared with aloe vera leaf extract and several antibiotics against antibiotic-resistant Shigella and Salmonella bacteria. These bacteria were obtained from Kirkuk General Hospital and re-diagnosed based on reliable diagnostic sources. According to the study, aloe vera leaf extract reduces silver ions while changing the color of the solution to reddish brown. The silver nanoparticles produced by the aloe vera plant were detected using a UV-visible spectrophotometer and found to fall at wavelengths (430( nm The results of (111), (200), and (220) indicate that silver particles and antibiotic tablets extracted from aloe vera leaves (amoxicillin, chloramphenicol, erythromycin, and ciprofloxacin) have synergistic effects against drug-resistant bacteria such as shigella and salmonella. As a result, their antimicrobial efficacy was enhanced.