Evaluating the role of arginine deaminase and its relationship with the development of diabetes in patients with non-alcoholic fatty liver disease

The study included the results obtained from examining (160) samples of blood serum for two groups: the control group, which included (80) samples, and the group of patients with non-alcoholic fatty liver disease (NAFLD), which included (80) samples. The groups were divided according to age into two age groups that included (less than 45) and (More than 45 years) and according to body mass index into obese (BMI greater than 25) and non-obese (BMI between 18 and 25) and according to gender into females and males. In addition to classifying patients into two groups: a group of treated patients and a group of newly diagnosed and untreated NAFLD patients, the study included estimating the activity of the enzyme arginine deaminase type 4 (ADI4) and the levels of some biochemical variables, which included total cholesterol T.C., triglycerides TG, and high-density lipoprotein cholesterol HDL-C, low-density LDL-C, very low-density VLDL-C, and glycated hemoglobin HbA1c. The results indicated an inverse relationship between the activity of ADI4 and HbA1c.