New Complexes of Nickel (II) with Mixed Ligands(2-oxime-4-(hydroxl benzilidine)pentane and (Thiosemicarbazones) and (Glycine) or(Metformine),Evaluation of Biological Activites and laser Irradiation

New nickel (II) complexes with three mixed ligand {which are 2-Oxime-4 (3- hydroxyl benzlidene) pentane (L2H); 2- chloro benzaldehyde- thiosemicarbazone (T1H) or 3,4- dimethoxy aceto-phenone thiosemicarbazone (T2H); and glycine (GH) or metformin (mf)} have been prepared by applying classical and microwave heating techniques. The resulting compounds have been characterized using analytical, physical and spectral techniques. Complexes of general formulaes [Ni(L2H)(TH)(BH)](Ac)2 in slightly neutral medium and complexes of general formula [Ni(L2)(T)(mf)] and [Ni(L2)(TH)(G)] in basic medium have been resulted. {where BH= GH or mf ligand, TH= T1H or T2H ligand, L2= deprotonated L2H ligand, T= deprotonated T1H or T2H ligand, G= deprotonated GH ligand}, high spin octahedral complexes have been resulted. No laser He-Ne type (wave length are 600- 700 nm) have been observed on the compounds, this means that the compounds are stable. Biological activity of the ligands and complexes have been evaluated using agar plate diffusion technique against Echerichia coli, Klipsila pnnemoia, Staphylococcus aureus and Pseudomonas aeruginosa. Some compounds were found to have antibacterial activity.