Volume 20 Issue 2
Published: 2025-06-25
Contents
Research Paper
Scanning Sildenafil Citrate Solubility in Hydrotropic Solutions
Ebtissam Ameer Al-dulaimi, Mohanad A. Alfahad, Mohannad Emad Qazzaz,
Background: Sildenafil citrate (SC) is a selective phosphodiesterase-5 inhibitor with low aqueous solubility (4.1 mg/mL in water), resulting in only 40% bioavailability after oral administration....
COVID-19 and Hand Hygiene: Has the Pandemic Heightened Mothers’ Awareness in Quetta City, Pakistan?
Harith Al-Qazaz, Sadeel Shanshal, Fahad Saleem, Qaiser Iqbal, Sajjad Haider, Sameera Mohammad
Background: Supported by evidence-based literature, hand hygiene (HH) is one of the cost-effective and simple preventive measures against COVID-19. The phenomenon is least reported in the...
Bacterial Profile and Antibiotic Susceptibility Pattern of Uropathogens Causing Urinary Tract Infections in Quetta City, Pakistan
Harith Al-Qazaz, Sadeel Shanshal, Palwasha Khan Kakar, Fahad Saleem, Qaiser Iqbal, Sajjad Haider
Background: Irrational use of antibiotics and antibiotic resistance against uropathogens is a global catastrophe. Consequently, it is necessary to identify the antibiotic susceptibility pattern of...
Review Paper
Doxorubicin Cardiotoxicity: An Update Regarding the Mechanism of Toxicity and Mitigation Strategies of Bee Propolis
Mohanad A. Alfahad, Mohannad E Qazzaz, Hodhaifa Abdul Mohsin
Introduction: Doxorubicin (Dox.) is a very effective antineoplastic agent for treating various tumours. It produces an anti-cancer mechanism through the intercalation of DNA and reducing...
Is Nefopam Effective in Treating Acute Renal Colic? A Narrative Review
Mohammed Ibrahim Aladul, Rima A Hijazeen, Zainab Mohammed Al-Shammaa, Ashraf Ibrahim Aldool
AbstractBackground: Acute renal colic is a severe and sudden form of loin pain that usually radiates from the flank towards the groin. Acute renal colic is one of the common causes of emergency...
Effects of Epigallocatechin-3-Gallate (EGCG) in Diabetes Mellitus as a DYRK1A inhibitor
Doaa Khalid Ibrahim, Nooralhuda Akram Yahya,
Background: Diabetes mellitus is a common metabolic disorder characterized by chronic high blood sugar levels due to impaired insulin secretion or action. Existing diabetic medications have...
The Influence of Dioxolane Ring Conjugates on Biological Activities: A Review Study
Yasser Fakri Mustafa, Ahmed A. J. Mahmood, Moath Kahtan Bashir, Mahmood Khudhayer Oglah,
Background: The problem of drug side effects necessitates the design, synthesis, and development of novel therapeutic agents that possess high activity with minimal side effects. According to the...
Thionyl Chloride: A Catalyst of Synthetic Chemical Interest
Yasser Fakri Mustafa, Noor Ahmed Waheed, Noora Thamer Abdulaziz, Sawsan Hasan Hammodi
Background: Particularly developed ingredients that are easily manufactured and utilized for additional exploitation are used in organic synthetic chemistry. Thionyl chloride serves as a...
Coumarin-Based Derivatives: A Review of Their Synthetic Routes, Reactivity, and Biomedical Attributes
Yasser Fakri Mustafa, Rana Naeem Jibroo, Wejdan Al-Shakarchi
Background: Coumarin-based derivatives (Cou-Ds) are one of the most important types of heterocycles, with a wide range of uses in synthetic and medicinal chemistry. Cou-Ds have interested...
Bell Pepper Biowaste Products as Medicinally Valuable Nutraceuticals: A Comprehensive Review
Yasser Fakri Mustafa, Areej Hazem Alyamoor
Background: The numerous additional valued substances present within plant biowaste products have a wide range of candidates regarding their recycling, promoting the idea of the circular economy....
