Effect of Green Tea on Development of Atherosclerogenic Lesions Induced by Experimentally Hydrogen Peroxide in Female Rat Experimental
Abstract
This study was conducted to investigate the ability of green tea asantioxidant and antiatherogenic in female rats after treated with 0.5o/o ofH20 2 in order to induced atherosclerosis. The results showed capability ofH20 2 0.5% to initiate of oxidative stress via significant increase in tissueMDA in aorta and heart associated with decrease in GSH, as well as,increase in ijDL-c and decrease in LDL-c in serum of treated rats.Histologically, aorta and heart sections revealed less improvement inhistological picture, reduction lipid vacuoles in both intimal and mediallayers associated with proliferation of vascular smooth muscle cells but itnot reach to normal tissue.