Synthesis of Some Heterocyclic Compounds Derived From 2-Amino Benzothiazole

Section: Research Paper
Published
Dec 1, 2020
Pages
193-205

Abstract

In this thesis, Anmber of heterocylic compound with five and six memberd, Such as substituted imidazole, triazin and thiazolidine. The N-(1,3-benzothiazol-2-yl)-2-chloro acetamide compound(1) was prepared from the reaction of the compound (2-amino benzothiazole) with chloroacetyl chloride. The product(1) was reacted with thiourea and urea to prepare both (imidazole -2-thione (2) and imidazole -2-one(3)) , respectively. As did compound(1) with thiosemicarbazide and semicarbazide to prepared the two compounds (1,2,4-triazine -3-thione (4) and 1,2,4-triazine -3-one (5)) ,respectively. Also compound(1) with ammonium thiocyanate to prepare the compound thiazolidin -4-one (6). From the reaction of compound(1) with phenyl thiourea attended imidazole -2-thione(7). Also from the reaction of (2-amino benzothiazole) with phthalic anhydride or malic anhydride attended compounds (8) and (9) ,respectively. And by reaction compound(8) or (9) with o-phenylene diamine attended compounds (10) and (11) ,respectively. The synthesized compounds are identified by physical (melting points, colour change) and spectral methods such as (IR, proton-NMR).

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How to Cite

[1]
Z. Muataz Mahmood, زینب, A. Kh. Ahmad, and احمد, “Synthesis of Some Heterocyclic Compounds Derived From 2-Amino Benzothiazole”, EDUSJ, vol. 29, no. 4, pp. 193–205, Dec. 2020.