Synthesis of Spiro Pyrrolidines From the Addition of Schiff Bases to -Arylidene Cyclohexanones

Section: Article
Published
Jun 1, 2008
Pages
19-27

Abstract

ABSTRACT A series of -arylidene cyclohexanones (1-4) had been prepared via Claisen-Schmidt condensation, while other series of N-arylidene benzylamines (Schiff bases 5-10) had also been synthesized by equimolar addition. The 1,3-anionic cycloaddition of Schiff bases to -arylidene cyclohexanones under basic conditions afforded the corresponding spiro pyrrolidines (11-23). The structures of the products are supported by valid spectral data and physical properties. Theoretical data had been used to support the suggested mechanism.

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How to Cite

[1]
A. Al-Hamdany, عبدالوهاب, A. Mustafa, أ., Hamza ِ., and أ., “Synthesis of Spiro Pyrrolidines From the Addition of Schiff Bases to -Arylidene Cyclohexanones”, EDUSJ, vol. 21, no. 2, pp. 19–27, Jun. 2008.