The Effect of Age, Smoking and Exercise on Sorbitol Dehydrogenase and its Correlation Factor with Some Biochemical Variables in Diabetics

ABSTRACT This research includes a biochemical study of sorbitol dehydrogenase (SDH) in the serum of the control and patient with diabetes mellitus. Their ages ranged between (8-65year) . It has been shown that the mean value of (SDH) activity is (0.015 0.010) of the control group and )0.5160917) of the patient groups .The result shown that significant increase in activiyof (SDH) patient groups and for each sexes when compared with control groups .There was a study of the relationship between (SDH) activity and clinical variables of the control and patient groups by finding the linear correlation was studied. Moreover , there was positive significant correlation between the activity of enzyme and each of glucose , total protein , albumin , globulin , in control and patient groups . Inverse significant correlation between the activity and Ca++ in control and patient groups .