Morphological effect of Ceftriaxone on Pseudomonas aeruginosa and Proteus mirabilis

ABSTRACT The effect of ceftriaxone on the morphology of Pseudomonas aeruginosa and Proteus mirabilis was investigated by incubating the bacterial suspensions with serial doubled concentrations of the antibiotics for (4) hrs. The results showed that ceftriaxone induces obvious morphological changes in the tested bacteria. Cell elongation and filamentation, with various levels, were the most frequent changes observed. The study also found that these morphological changes depend on the antibiotic concentration.