Using The Interaction of Sodium Nitroprusside With Modecate And Tegretol, As an Indirect Method For Their Determination Using S.W.V. Technique

Abstract A square wave voltammetric (S.W.V.) method has been developed for the quantitative analysis of sodium nitroprusside (SNP), sodium nitroprusside gives a peak at (-0.592) volt against the reference electrode (Ag/AgCl/sat KCl) in phosphate buffer (pH= 7.0). A calibration curve was constructed for the range [(0.99 x 10-7-(14.77 x 10-7)]M the method was applied for indirect determination of medicate and tegretol individually via the interaction of SNP with these drugs. So, a calibration curve was constructed by adding appropriate amounts of modecate of the range [(9.84 x 10-11 1.360 x 10-9)] M in the presence of (14.77 x 10-6)M SNP. An other calibration curve was constructed by adding appropriate amounts of tegretol of the range [(9.89 x 10-11 9.8 x 10-10)] M in the presence of (9.9 x 10-6)M of SNP.