effect of seeds alcoholic extract of Nigella sativa in some blood biochemical varieties of male rats exposed to oxidative stress

ABSTRACT This work designed to determine the effect of watery extract of Nijella sativa in induced oxidative stress by hydrogen peroxide (0.5%) in male rats on some biochemical parameters of blood. The results showed giving male (0.5%) hydrogen peroxide with drinking water lead to increase in level of cholesterol, triglycerides, low density lipoproteins significantly (P<0.05) comparing with control group and decreases in level of high density lipoprotein significantly (P<0.05) with compare of control group also. Treating male rats that have oxidative stress by watery extract of N. sativa 100 mg/kg of B.W showed significant decrease in level of Glucose, Cholesterol, Triglyceride comparing with hydrogen peroxide group. We conclude from the result of this study that the watery extract of N. sativa have important role in restricting the effects of free radical inside the body.